<select name="name">
<option disabled="disabled" selected="selected">Select an option.</option>
<option>A</option>
<option>B</option>
<option>C</option>
</select>
<select>
<option hidden>Choose</option>
<option>Item 1</option>
<option>Item 2</option>
</select>
<!-- disable form first dropdown option -->
<script type="text/javascript">
$( "form option:first-child" ).attr("disabled","disabled");
</script>